Researches

Download US FDA report on Johnson & Johnson’s single dose COVID-19 vaccine

The COVID-19 vaccine by Johnson & Johnson is on track to become the latest vaccine in the global fight against COVI-19. Today (Wednesday), the US FDA released its report on the vaccine and you can read the entire 62 pages below. FDA-Briefing-Document According to the document, in the study that involved about 40,000 participants, as of February 5, 2021, there were 7 COVID-19 related deaths in the study in the placebo group and no COVID-19-related

Africa’s first Lassa fever vaccine clinical trial begins in Ghana

INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases and cancer, today announced the first participant was dosed in a Phase 1B clinical trial for INO-4500, its DNA vaccine candidate for Lassa fever, in Ghana. The Phase 1B clinical trial (LSV-002), ongoing at the Noguchi Memorial Institute for Medical Research in Accra, Ghana, is the first vaccine clinical trial for Lassa Fever to be conducted in West

Pooled COVID-19 tests may offer more efficient surveillance while maintaining sensitivity

Pooled testing for COVID-19 can maintain the accuracy of test results while reducing the use of testing resources by as much as 76%, according to two new studies of nasopharyngeal test samples. Widespread testing is critical to manage the ongoing COVID-19 pandemic, as it allows authorities to trace the spread of SARS-CoV-2 and implement effective mitigation measures. However, testing large populations with individual tests is resource-intensive, and breakdowns in supply chains and limitations on testing speeds have severely held back

New drug outperforms PreP in preventing HIV among African women

The Joint United Nations Programme on HIV/AIDS (UNAIDS) has announced that it is strongly encouraged by new study results showing that the antiretroviral medicine cabotegravir, which is administered by injection every two months, prevents HIV among women. The study shows that the long-acting injections among women in sub-Saharan Africa were 89% more efficient in preventing HIV compared to daily tablets of pre-exposure prophylaxis (PrEP). “These results are hugely significant. UNAIDS has long been calling for additional, acceptable and effective HIV prevention options

There is a promising vaccine candidate for herpes

A genetically edited form of a herpes simplex virus — rewired to keep it from taking refuge in the nervous system and eluding an immune response — has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln. Published Nov. 6 in the journal Nature Vaccines, the study found that vaccinating guinea pigs with the modified live virus significantly increased the production of virus-combating antibodies. When challenged with a virulent strain

Drugs for HIV, hepatitis could prevent type 2 diabetes – study

A group of drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes, a new study suggests. Researchers found that patients taking the drugs had a 33% lower risk of developing diabetes. The scientists say that the risk reduction makes sense based on how the drugs are known to work, and noted that one of the drugs, lamivudine, improved insulin sensitivity significantly in human cell samples and in a mouse model of diabetes. (In type