Researches

Hope for people co-infected with visceral leishmaniasis and HIV

Today, the World Health Organization (WHO) has released its guidelines for the treatment of people co-infected with visceral leishmaniasis and HIV, to recommend better treatments based on the results of two studies conducted by the Drugs for Neglected Diseases initiative (DNDi), Médecins Sans Frontières (MSF) and their partners in Ethiopia and India. In Ethiopia, the new treatment strategy was shown to have an 88% efficacy rate at the end of therapy (after 58 days), whereas the efficacy

What we know about the origin of DRC’s latest Ebola outbreak

On April 23, 2022, the Minister of Public Health, Hygiene, and Prevention announced a new case of Ebola virus disease (EVD) occurring in Mbandaka health zone in Equateur Province, Democratic Republic of the Congo (DRC). EVD outbreaks occurred previously in Equateur Province in 2018 and 2020. The 31-year-old male, a student from Boende in Tshuapa Province, returned to Mbandaka, Equateur Province on February 25, 2022. He was vaccinated against Ebola virus in 2020 and is not known to be an EVD

WHO recommends against the use of convalescent plasma to treat COVID-19

The World Health Organization (WHO) has updated its living guideline on COVID-19 therapeutics to include convalescent plasma. For non-severe COVID-19 patients, WHO recommends against its use, while it should only be used within clinical trials for severe and critical COVID-19 patients. Convalescent plasma is a transfusion of blood plasma from someone who has recovered from COVID-19. Current evidence shows that convalescent plasma does not improve survival or reduce the need for mechanical ventilation, while it has significant costs. An independent panel of experts,

More than 1 in 5 of all childbirths now through cesarean section — WHO

The rising rates of caesarean section suggest increasing numbers of medically unnecessary, potentially harmful procedures, the World Health Organisation (WHO) says. According to new research from the World Health Organization (WHO), caesarean section use continues to rise globally, now accounting for more than 1 in 5 (21%) of all childbirths. This number is set to continue increasing over the coming decade, with nearly a third (29%) of all births likely to take place by caesarean section by 2030, the research finds. While

Five ways to tackle vaccine hesitancy

The reluctance or refusal to accept Covid-19 vaccinations can be tackled by a five-pronged strategy to addressing the behavioural and socio-demographic factors behind vaccine hesitancy. Writing in the Journal of the Royal Society of Medicine, a group of population health, demographic, epidemiology and behavioural scientists propose an approach focused on confidence, complacency, convenience, communication and context. While confidence in the safety and efficacy of vaccines is crucial, they write, complacency, particularly among younger people and those of lower socioeconomic status, is

BMI may not be best obesity indicator to assess risk for lung cancer

New research published in the Journal of Thoracic Oncology (JTO) suggests the method used to calculate how obesity is measured may affect whether it is considered a risk factor for lung cancer. The JTO is an official journal of the International Association for the Study of Lung Cancer. Although the association between measures of obesity and both cancer incidence and outcome are clear in some solid tumor types such as breast, esophageal, and colon cancer, the relationship between obesity and lung cancer is

What most Nigerian women get wrong about abortion

A recent study showed drug sellers were the only source of information about misoprostol for three-quarters of the 400 women aged 18–49 who self-managed an abortion using misoprostol. The study found that most women who participated in the study did not receive adequate or accurate information about how to administer misoprostol, how much to use, or what to expect during the abortion process. For example, only 67% of participants were told to anticipate bleeding and 35% were told to expect cramping,

Download US FDA report on Johnson & Johnson’s single dose COVID-19 vaccine

The COVID-19 vaccine by Johnson & Johnson is on track to become the latest vaccine in the global fight against COVI-19. Today (Wednesday), the US FDA released its report on the vaccine and you can read the entire 62 pages below. FDA-Briefing-Document According to the document, in the study that involved about 40,000 participants, as of February 5, 2021, there were 7 COVID-19 related deaths in the study in the placebo group and no COVID-19-related

Africa’s first Lassa fever vaccine clinical trial begins in Ghana

INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases and cancer, today announced the first participant was dosed in a Phase 1B clinical trial for INO-4500, its DNA vaccine candidate for Lassa fever, in Ghana. The Phase 1B clinical trial (LSV-002), ongoing at the Noguchi Memorial Institute for Medical Research in Accra, Ghana, is the first vaccine clinical trial for Lassa Fever to be conducted in West

Pooled COVID-19 tests may offer more efficient surveillance while maintaining sensitivity

Pooled testing for COVID-19 can maintain the accuracy of test results while reducing the use of testing resources by as much as 76%, according to two new studies of nasopharyngeal test samples. Widespread testing is critical to manage the ongoing COVID-19 pandemic, as it allows authorities to trace the spread of SARS-CoV-2 and implement effective mitigation measures. However, testing large populations with individual tests is resource-intensive, and breakdowns in supply chains and limitations on testing speeds have severely held back